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Early births, onset of periods may increase risk of cardiovascular disease

Written by  Shefali Kohli -- February 27th 2023 07:12 PM
Early births, onset of periods may increase risk of cardiovascular disease

Early births, onset of periods may increase risk of cardiovascular disease

London: According to the new study and research, earlier first births, more live births, and earlier onset of periods are all associated with an increased risk of cardiovascular issues in women.

The study stated that casual link between sex-specific risk variables and cardiovascular disease in women and suggests prospective mitigation strategies.


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Linkage between reproductive factors and cardiovascular disease may cause atrial fibrillation (irregular heartbeat), coronary heart disease, heart failure, and stroke. The researchers anticipate that this will enable physicians to more effectively assess, track, and intervene as necessary in women's risk factors.

Observational research has previously identified that some reproductive factors are associated with cardiovascular disease for women in later life, but such studies are limited as they have been unable to support a causal relationship.

The researchers were able to show a link between the genes that predict reproductive factors and the risk of multiple cardiovascular diseases. This type of analysis enables researchers to cut through the noise of factors such as diet, economic background and physical activity levels that can otherwise complicate the overall picture, and so it points to causal links.

The analysis showed that earlier first birth, a higher number of live births, and earlier menarche were associated with a higher risk of atrial fibrillation, coronary artery disease, heart failure, and stroke in women. However, it did not find an association between the age of menopause and cardiovascular disease.

 Further research is needed to understand the extent of the relationship between reproductive factors and cardiovascular disease risks, such as whether there is a linear or non-linear relationship between a factor and increased risk.

Research by the British Heart Foundation has shown that coronary heart disease kills more than twice as many women as breast cancer in the UK each year, with more than 8,00,000 women in the UK living with the disease. It is also estimated that around 3,80,000 women alive in the UK today have survived a heart attack.

Meanwhile, the misconception that cardiovascular disease mostly affects men is costing women their health, and even their lives.

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The study also stated that,  it's critical that women are empowered with the knowledge of what could put them at higher risk of developing heart disease or stroke in the future. This includes the well-known risks that affect everyone - but for women, there may be additional risk factors from their reproductive years to add to the list.

- ANI

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