The US company Novavax said that its COVID-19 vaccine, in the Phase 3 trial, demonstrated an overall efficacy of 90.4 percent against mild, moderate, and severe disease caused by the COVID-19 strain.

"Novavax COVID-19 Vaccine demonstrates 90% overall efficacy and 100% protection against moderate and severe disease in PREVENT-19 Phase 3 Trial," the company said in a tweet.
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While releasing its Phase 3 trial details, the company said that the preliminary safety data from PREVENT-19 showed the vaccine to be generally well-tolerated.
Serious and severe adverse events were low in number and balanced between vaccine and placebo groups, it said, adding that no single adverse event term was reported by more than 1 percent of participants.
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PREVENT-19 Phase 3 Trial, Novovax COVID-19 Vaccine Candidate Demonstrates:
- 90% overall efficacy
- 93% efficacy against predominantly circulating Variants of Concern and Variants of Interest
- 91% efficacy in high-risk populations
- 100% protection against moderate and severe disease
- 100% efficacy against variants "not considered Variants of Concern/Interest"

Stanley C. Erck, President and Chief Executive Officer, Novavax, said that "Novavax is one step closer to addressing the critical and persistent global public health need for additional COVID-19 vaccines."
Biotech firm is planning to file for authorisation with the Food and Drug Administration in the third quarter of 2021.
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